Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3294214 | Gastroenterology | 2010 | 9 Pages |
Abstract
We have identified autoantibodies against α-enolase in a mouse model of BA (infected with RRV) and in serum samples from patients, indicating a role of humoral autoimmunity in disease pathogenesis. The cross-reactivity between an anti-enolase antibody and RRV proteins indicates that molecular mimicry might activate humoral autoimmunity in BA patients; further studies are required.
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Authors
Brandy R. Lu, Stephen M. Brindley, Rebecca M. Tucker, Cherie L. Lambert, Cara L. Mack,