| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3294464 | Gastroenterology | 2010 | 13 Pages |
Abstract
Nanoparticles are a versatile drug delivery system that can overcome physiologic barriers and target anti-inflammatory agents such as the peptide KPV to inflamed areas. By using NPs, KPV can be delivered at a concentration that is 12,000-fold lower than that of KPV in free solution, but with similar therapeutic efficacy. Administration of encapsulated drug-loaded NPs is a novel therapeutic approach for IBD.
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Authors
Hamed Laroui, Guillaume Dalmasso, Hang Thi Thu Nguyen, Yutao Yan, Shanthi V. Sitaraman, Didier Merlin,