| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3294477 | Gastroenterology | 2010 | 15 Pages |
Abstract
TGF-β/Smad signaling suppresses progression and metastasis of CRC cells and tumors in mice. Loss of Smad4 might underlie the functional shift of TGF-β from a tumor suppressor to a tumor promoter; inhibitors of TGF-β signaling might be developed as CRC therapeutics.
Keywords
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Authors
Bixiang Zhang, Sunil K. Halder, Nilesh D. Kashikar, Yong-Jig Cho, Arunima Datta, D. Lee Gorden, Pran K. Datta,