Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3294479 | Gastroenterology | 2010 | 11 Pages |
Abstract
Msh2LoxP/LoxP mice in combination with appropriate Cre recombinase transgenes have excellent potential for preclinical modeling of Lynch syndrome, MMR-deficient tumors of other tissue types, and use in drug development.
Keywords
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Gastroenterology
Authors
Melanie H. Kucherlapati, Kyeryoung Lee, Andrew A. Nguyen, Alan B. Clark, Harry Jr, Andrew Rosulek, Hua Li, Kan Yang, Kunhua Fan, Martin Lipkin, Roderick T. Bronson, Linda Jelicks, Thomas A. Kunkel, Raju Kucherlapati, Winfried Edelmann,