| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3294564 | Gastroenterology | 2012 | 18 Pages |
Abstract
Here we describe a novel mechanism for NFATc2-mediated gene regulation and identify a functional link among its repressor activity, the silencing of the suppressor pathway p15INK4b, and its pancreatic cancer growth regulatory functions. Thus, we provide evidence that inactivation of oncogenic NFATc2 might be an attractive strategy in treatment of pancreatic cancer.
Keywords
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Gastroenterology
Authors
Sandra Baumgart, Elisabeth Glesel, Garima Singh, Nai-Ming Chen, Kristina Reutlinger, Jinsan Zhang, Daniel D. Billadeau, Martin E. Fernandez-Zapico, Thomas M. Gress, Shiv K. Singh, Volker Ellenrieder,