Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3294607 | Gastroenterology | 2009 | 15 Pages |
Abstract
Synchronous colorectal cancers had more frequent mutations in BRAF, were more frequently CIMP- and MSI-high, and had a worse prognosis than solitary colorectal cancers. Similar epigenomic and epigenetic events were frequently observed within a synchronous cancer pair, suggesting the presence of a field defect.
Keywords
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Authors
Katsuhiko Nosho, Shoko Kure, Natsumi Irahara, Kaori Shima, Yoshifumi Baba, Donna Spiegelman, Jeffrey A. Meyerhardt, Edward L. Giovannucci, Charles S. Fuchs, Shuji Ogino,