| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3294627 | Gastroenterology | 2009 | 15 Pages |
Abstract
This study provided a mechanism for the generation of protumorigenic ÎEx2p73 during liver tumorigenesis, via activation of EGFR signaling by AR and c-Jun N-terminal kinase-1 activity, leading to inhibition of the splicing regulator Slu7.
Keywords
PEDFp53 up-regulated modulator of apoptosisAquaporin 3AQP3JnkEGFRPI3Kc-Jun N-terminal kinaseHCCSmall interfering RNAsiRNAADAMchromatin immunoprecipitation assayamphiregulinactinomycin Da disintegrin and metalloproteinasetransactivation domainCirrhoticPigment Epithelium Derived Factorphosphatidylinositol-3-kinaseAct DPUMACHiPHepatocellular carcinomaEpidermal growth factor receptor
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Authors
Josefa Castillo, Saioa Goñi, MarÃa Ujue Latasa, MarÃa J. PerugorrÃa, Alicia Calvo, Jordi Muntané, Paulette Bioulac-Sage, Charles Balabaud, Jesús Prieto, MatÃas A. Avila, Carmen Berasain,