Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3294628 | Gastroenterology | 2009 | 21 Pages |
Abstract
Ubiquitination and proteasome degradation of P21WAF1, P27KIP1, P57KIP2, P130, RASSF1A, and FOXO1 and mechanisms that prevent degradation of SKP2 by APC/C-CDH1 contribute to HCC progression. CKS1-SKP2 ligase might be developed as a therapeutic target or diagnostic marker.
Keywords
Related Topics
Health Sciences
Medicine and Dentistry
Gastroenterology
Authors
Diego F. Calvisi, Sara Ladu, Federico Pinna, Maddalena Frau, Maria L. Tomasi, Marcella Sini, Maria M. Simile, Piero Bonelli, Maria R. Muroni, Maria A. Seddaiu, Dae-Sik Lim, Francesco Feo, Rosa M. Pascale,