| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3294782 | Gastroenterology | 2009 | 16 Pages |
Abstract
Our results show that deletion of c-Met in hepatocytes leads to more liver cell damage and fibrosis in a chronic cholestatic liver injury model because c-Met triggers survival signals important for hepatocyte recovery.
Keywords
HSCTNFTNFAIP3MMP-13mesenchymal-epithelial transition factorPDGF-DHGFTIMP-1DAPIBDLIKKTLRSTAT36-diamidino-2-phenylindolec-Metα-fetoproteinBrdUbromodeoxyuridineterminal deoxynucleotidyl transferase–mediated deoxyuridine triphosphate nick-end labelingAFPTUNELToll-like receptorHepatic stellate cellHepatocyte growth factortumor necrosis factorTRAILTNF-related apoptosis-inducing ligandMatrix metalloproteinase 13signal transducer and activator of transcription 3bile duct ligation
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Authors
Arne Giebeler, Mark V. Boekschoten, Christian Klein, Malgorzata Borowiak, Carmen Birchmeier, Nikolaus Gassler, Hermann E. Wasmuth, Michael Müller, Christian Trautwein, Konrad L. Streetz,