Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3294848 | Gastroenterology | 2009 | 12 Pages |
Abstract
These results indicate that FoxO4 is an endogenous inhibitor of NF-κB and identify a novel function of FoxO4 in the regulation of NF-κB-mediated mucosal immunity.
Keywords
IκBT helper type 1Th1TNBSIRFIFNγNF-κBIL-1βIBDqRT-PCRTNFαLPSDMEMGFPIELFITCDulbecco's modified Eagle's mediumshort interfering RNAsiRNAElectrophoretic mobility shift assayTight junctionTrinitrobenzene sulfonic acidinterferon-γInterleukin-1βCrohn's diseaseInflammatory bowel diseasetumor necrosis factor-αEMSA یا electrophoretic mobility shift assay interferon regulatory factornuclear factor-κBFoxOfluorescein isothiocyanateIntraepithelial lymphocytelipopolysaccharideinhibitor κBknock-outwild-typequantitative reverse transcription polymerase chain reactiongreen fluorescent proteinUlcerative colitis
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Authors
Wen Zhou, Qian Cao, Yan Peng, Qing-Jun Zhang, Diego H. Castrillon, Ronald A. DePinho, Zhi-Ping Liu,