Article ID Journal Published Year Pages File Type
3294918 Gastroenterology 2011 11 Pages PDF
Abstract
Pancreatic inflammation significantly increased the expression and functional properties of TRPV1 and TRPA1, as well as the excitability of pancreatic sensory neurons in vagal and spinal pathways. TRP channel antagonists acted synergistically to reverse pancreatic inflammation and associated pain behaviors; reagents that target interactions between these channels might be developed to reduce pain in patients with acute pancreatitis.
Related Topics
Health Sciences Medicine and Dentistry Gastroenterology
Authors
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