Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3294922 | Gastroenterology | 2011 | 17 Pages |
Abstract
Dysregulated TFH cells in the spleen are responsible for the induction of fatal AIH, and CCR6-CCL20 axis-dependent migration of splenic T cells is crucial to induce AIH in NTx-PD-1â/â mice.
Keywords
PNAIL-21 receptorIL-21RRecombination activating gene 2ICOSfollicular helper TPD-LCXCRT helperTFHRag2TregsAIHPD-1APCEAENTXantinuclear antibodyexperimental autoimmune encephalomyelitispeanut agglutininANAimmunoglobulin interferonIFNinterleukinautoimmune liver diseaseFollicular helper T cellsRegulatory T cellsGerminal centerprogrammed cell death 1Autoimmune hepatitisPathogenesisInducible costimulatorCXC chemokine receptor
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Authors
Nobuhiro Aoki, Masahiro Kido, Satoru Iwamoto, Hisayo Nishiura, Ryutaro Maruoka, Junya Tanaka, Takeshi Watanabe, Yoshimasa Tanaka, Taku Okazaki, Tsutomu Chiba, Norihiko Watanabe,