Campylobacter jejuni Induces Colitis Through Activation of Mammalian Target of Rapamycin Signaling

Article ID	Journal	Published Year	Pages	File Type
3295450	Gastroenterology	2012	15 Pages	PDF

Abstract

mTOR signaling mediates C jejuni-induced colitis in Il10â/â mice, independently of T-cell activation. Factors involved in mTOR signaling might be therapeutic targets for campylobacteriosis.

Keywords

NF-κB MLN mTOR eGFP SPF CFU PI3K Tem interleukin Imaging specific pathogen-free nuclear factor κB phosphoinositide 3-kinase fluorescence in situ hybridization Fish Mouse model Transmission electron microscopy Signal transduction mammalian target of rapamycin colony-forming unit Immune response enhanced green fluorescent protein mesenteric lymph node