Article ID Journal Published Year Pages File Type
3295688 Gastroenterology 2011 14 Pages PDF
Abstract
MMP-9 mediates cellular inflammatory responses within the intestinal muscularis in mouse and rat models of POI. Inhibition of MMP-9 activity reduced recruitment of immune cells to the intestinal muscularis, preventing loss of smooth muscle contractility. Induction of MMP-9 expression requires inducible nitric oxide synthase.
Related Topics
Health Sciences Medicine and Dentistry Gastroenterology
Authors
, , , ,