| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3295690 | Gastroenterology | 2011 | 18 Pages |
Abstract
Deletion of Klf5 in the gut epithelium of mice demonstrated that KLF5 maintains epithelial proliferation, differentiation, and cell positioning along the crypt radial axis. Morphologic changes that occur with deletion of Klf5 are associated with disruption of canonical Wnt signaling and increased expression of Sox9.
Keywords
Related Topics
Health Sciences
Medicine and Dentistry
Gastroenterology
Authors
Beth B. McConnell, Samuel S. Kim, Ke Yu, Amr M. Ghaleb, Norifumi Takeda, Ichiro Manabe, Asma Nusrat, Ryozo Nagai, Vincent W. Yang,