Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3296103 | Gastroenterology | 2010 | 13 Pages |
Abstract
Targeted inactivation of SR pathways reduces the hepatic inflammation and tissue destruction associated with NASH, independent of hepatic foam cell formation.
Keywords
NF-κBnuclear factor κ-BTGF-βTNFMDAOil Red O stainingoxLDLHFCOROCol1α1TLRPPARALTBCAABCAcLDLMSRMMPFFAcDNAMPOComplementary DNAAcetylated LDLOxidized LDLASTAspartate aminotransferaseAlanine aminotransferaseApoeapolipoprotein Enonalcoholic steatohepatitisFree fatty acidinflammationimmunoglobulin bicinchoninic acidTransforming growth factor βTriglyceridesToll-like receptorTIMPKupffer cellsKupffer celltumor necrosis factorLow-density lipoproteinLDLMatrix metalloproteasemalondialdehydeTissue inhibitor of metalloproteinasemyeloperoxidaseNash transplantedAdenosine triphosphate binding cassetteFatty livertotal cholesterolPeroxisome proliferator activated receptorScavenger receptorsMacrophage scavenger receptor
Related Topics
Health Sciences
Medicine and Dentistry
Gastroenterology
Authors
Veerle Bieghs, Kristiaan Wouters, Patrick J. van Gorp, Marion J.J. Gijbels, Menno P.J. de Winther, Christoph J. Binder, Dieter Lütjohann, Maria Febbraio, Kathryn J. Moore, Marc van Bilsen, Marten H. Hofker, Ronit Shiri-Sverdlov,