Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3296157 | Gastroenterology | 2011 | 14 Pages |
Abstract
In patients with CHC, the viral-vector-based vaccine TG4040 had a good safety profile, induced HCV-specific cellular immune responses, and reduced viral load. This vaccine should be investigated in further clinical studies, in combination with standard of care.
Keywords
PHAPhytohaemagglutininALTCEFADRCHCPBMCserum alanine aminotransferasestandard of careinterferonIFNinterleukinViral loadLiver diseaseperipheral blood mononuclear cellsT helper cellSOCadverse eventAdverse drug reactionnonstructuralMVAImmunitychronic hepatitis Cplaque-forming unitsModified vaccinia AnkaraTherapeutic vaccinevirologypfu
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Authors
François Habersetzer, Géraldine Honnet, Christine Bain, Marianne Maynard-Muet, Vincent Leroy, Jean-Pierre Zarski, Cyrille Feray, Thomas F. Baumert, Jean-Pierre Bronowicki, Michel Doffoël, Christian Trépo, Delphine Agathon, Myew-Ling Toh,