Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3296165 | Gastroenterology | 2011 | 18 Pages |
Abstract
DOR localizes specifically to submucosal and myenteric neurons, which might account for the ability of DOR agonists to inhibit gastrointestinal secretion and motility. Sustained down-regulation of DOReGFP at the plasma membrane of activated neurons could induce long-lasting tolerance to DOR agonists.
Keywords
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Authors
Daniel P. Poole, Juan-Carlos Pelayo, Gregory Scherrer, Christopher J. Evans, Brigitte L. Kieffer, Nigel W. Bunnett,