| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3296460 | Gastroenterology | 2011 | 13 Pages |
Abstract
Ingestion of deamidated gliadin induces differentiation of tolerogenic, type 1 regulatory T cells in spleens of HLA-DQ2 transgenic mice. These data indicate that under homeostatic conditions, the T-cell response to deamidated gliadin is tolerance, which is not conditioned by the mucosal immune system but instead requires interleukin-10 induction by antigen presentation in the spleen.
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Authors
M. Fleur Du Pré, Anne E. Kozijn, Lisette A. van Berkel, Mariëtte N.D. ter Borg, Dicky Lindenbergh-Kortleve, Lise Torp Jensen, Yvonne Kooy-Winkelaar, Frits Koning, Louis Boon, Edward E.S. Nieuwenhuis, Ludvig M. Sollid, Lars Fugger,