Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3296469 | Gastroenterology | 2011 | 17 Pages |
Abstract
Cellular redox balance affects Wnt-β-catenin signaling, which protects against hypoxia and I/R injury. These findings might be used to develop strategies for protection of hepatocytes, regeneration of liver, and inhibition of carcinogenesis.
Keywords
DCF-DADMEMhpfTTATCFHREHIFK18LAP3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideDulbecco's modified Eagle MediumH/RI/RMTTROSLiver Damageischemia-reperfusionterminal deoxynucleotidyl transferase–mediated deoxyuridine triphosphate nick-end labelingTUNELdihydroethidiumdichlorofluorescein diacetateT-cell factorlymphoid enhancer factorhypoxia response elementVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)Hypoxia Inducible FactorHypoxia-reoxygenationLefhigh-power fieldDHEpolymerase chain reactionPCRkeratin 18Reactive oxygen species
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Authors
Nadja Lehwald, Guo-Zhong Tao, Kyu Yun Jang, Michael Sorkin, Wolfram T. Knoefel, Karl G. Sylvester,