| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3296470 | Gastroenterology | 2011 | 19 Pages |
Abstract
In mice, Rac1 is required for early metaplastic changes and neoplasia-associated actin rearrangements in development of pancreatic cancer. Rac1 might be developed as a diagnostic marker or therapeutic target for PDAC.
Keywords
ADMCytDCK19TGFRac1Latrunculin AEGFRPancreatic ductal adenocarcinomaPDAC یا pancreatic ductal adenocarcinomaBrdUbromodeoxyuridinecytochalasin Dcytokeratin 19Signalingtumor growth factorGenetically Engineered Micepancreatic intraepithelial neoplasiawild-typeLatAPanINCytoskeletonEpidermal growth factor receptor
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Authors
Irina Heid, Clara Lubeseder-Martellato, Bence Sipos, Pawel K. Mazur, Marina Lesina, Roland M. Schmid, Jens T. Siveke,