| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3296848 | Gastroenterology | 2010 | 12 Pages |
Abstract
HO-1 can interrupt progression of nutritional steatohepatitis by inducing an antioxidant pathway, suppressing production of cytokines, and modifying fatty acid turnover. Induction of HO-1 might provide a new approach for treatment of steatohepatitis.
Keywords
MIP-1αMCDHeme oxygenase-1IFN-γPPARαCRYABALTIP-10ACOHO-1GPXCyPmRNAacyl-CoA oxidaseSnMPLCADSREBP-1cFANCCcDNAComplementary DNAMOImessenger RNAROSAlanine aminotransferasenonalcoholic steatohepatitisinterferon-γinterleukintriglycerideLong-chain acyl-CoA dehydrogenaseCytochrome P450keratinocyte-derived cytokinemethionine- and choline-deficientcarbon monoxideNash polymerase chain reactionPCRmacrophage inflammatory proteinmultiplicities of infectionglutathione peroxidaseReactive oxygen species
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Authors
Jun Yu, Eagle S.H. Chu, Ruizhi Wang, Shiyan Wang, Chung W. Wu, Vincent W.S. Wong, Henry L.Y. Chan, Geofferey C. Farrell, Joseph J.Y. Sung,