| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3297032 | Gastroenterology | 2006 | 12 Pages |
Abstract
Conclusions: Our data show that antigen-specific CD8+ T cells can induce relapsing colitis in normal mice and suggest that the cytolytic function of CD8 Tc1 against epithelial cells may initiate the intestinal inflammatory process.
Keywords
SFCsCFSETNBSELISPOTDTHDNBSIFN-γIBDRT-PCRTc1CTLmAbFACSPBSq-PCRMonoclonal antibodyEnzyme-linked immunospotinterleukinCrohn’s diseaseInflammatory bowel diseasetumor necrosis factor αDelayed type hypersensitivityTNF-αfluorescence-activated cell sortercytotoxic T lymphocytePhosphate-buffered salinespot forming cellsquantitative polymerase chain reactionreverse-transcription polymerase chain reactionInterferon gamma
Related Topics
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Authors
Stéphane Nancey, Sébastien Holvöet, Ivan Graber, Grégoire Joubert, David Philippe, Stefan Martin, Jean-François Nicolas, Pierre Desreumaux, Bernard Flourié, Dominique Kaiserlian,