| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3297258 | Gastroenterology | 2011 | 17 Pages |
Abstract
In colon tissues of rodents, CRF2 activation inhibits CRF1 signaling in myenteric neurons and the stress-induced colonic motor responses. Disruption of CRF2 function impairs colonic coping responses to stress.
Keywords
giant migrating contractionsCRF1CRF2nNOSCRFGMCsHEKcorticotropin releasing factor receptor 1PRSLMMPWTLAUCERK1/2water avoidance stressUrocortin 1ImmunoreactivityWAShuman embryonic kidney cellsneuronal nitric oxide synthasecorticotropin releasing factorarea under the curveMyenteric neuronsNitric oxidepolymerase chain reactionPCRStress responselongitudinal muscle myenteric plexusextracellular signal-regulated kinase 1/2
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Authors
Guillaume Gourcerol, S. Vincent Wu, Pu-Qing Yuan, Hung Pham, Marcel Miampamba, Muriel Larauche, Paul Sanders, Tomofumi Amano, Agata Mulak, Eunok Im, Charalabos Pothoulakis, Jean Rivier, Yvette Taché, Mulugeta Million,