Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3297262 | Gastroenterology | 2011 | 28 Pages |
Abstract
High expression levels of CD151 and α6 promote invasiveness of HCC cells. Either of these proteins, or PI3K signaling, might be targets for therapeutics for subgroups of patients with HCC.
Keywords
TGFGSK-3PI3Kα-SMATMAshRNAERKqRT-PCRMAPKshort hairpin RNAAktα-smooth muscle actintransforming growth factorTumor invasionEMTLiver cancerphosphatase and tensin homologphosphatidylinositol-3-kinaselaminin 5MetastasisTissue microarrayquantitative real-time polymerase chain reactionprotein kinase BExtracellular regulated protein kinasemitogen-activated protein kinaseTumor progressionPtenEpithelial-mesenchymal transitionglycogen synthase kinase 3
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Authors
Ai-Wu Ke, Guo-Ming Shi, Jian Zhou, Xiao-Yong Huang, Ying-Hong Shi, Zhen-Bin Ding, Xiao-Ying Wang, Ranjan Prasad Devbhandari, Jia Fan,