Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3297413 | Gastroenterology | 2011 | 17 Pages |
Abstract
AnxA2 expression is required for the biologic effects of progastrin in vivo and in vitro and mediates the stimulatory effect of progastrin on p65NF-κ, β-catenin, and the putative stem cell markers DCAMKL+1 and CD44. AnxA2 might therefore mediate the hyperproliferative and cocarcinogenic effects of progastrin.
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Authors
Shubhashish Sarkar, Rafal Swiercz, Carla Kantara, Katherine A. Hajjar, Pomila Singh,