| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3297415 | Gastroenterology | 2011 | 16 Pages |
Abstract
β-NAD meets the criteria for a neurotransmitter better than ATP in human and monkey colons and therefore may contribute to neural regulation of colonic motility. SMCs are unlikely targets for inhibitory purine neurotransmitters because dominant responses of SMCs were activation of net inward, rather than outward, current.
Keywords
IJPADPRPPADScADPRFLCMRS2179TTXADPEFsβ-NADADOAMPHEPESSMCβ-nicotinamide adenine dinucleotideAdenosineadenosine 5′-triphosphateadenosine 5′-diphosphateadenosine 5′-monophosphateATPEnteric nervestetrodotoxinGastrointestinal motilityElectrical field stimulationGastrointestinalSmooth muscle cellFibroblast-like cellscircular muscleLongitudinal muscleinhibitory junction potentialhigh-pressure liquid chromatographyHPLCmyenteric gangliaP2Y receptors
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Authors
Sung Jin Hwang, Leonie Durnin, Laura Dwyer, Poong-Lyul Rhee, Sean M. Ward, Sang Don Koh, Kenton M. Sanders, Violeta N. Mutafova-Yambolieva,