| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3297718 | Gastroenterology | 2010 | 20 Pages |
Abstract
We identified a new, cytoprotective effect of FGFR1 and FGFR2 in the regenerating liver and suggest the use of recombinant FGF7 to increase survival of patients after surgical resection of large amounts of liver tissue.
Keywords
ALTFGFRTEFhLFFRS2αCCl4qRT-PCRFGFDBPCyP5-bromo-2′deoxyuridinePBSSTAT3ERK1/2ASTAspartate aminotransferaseAlanine aminotransferaseBrdULiver diseaseCytoprotectionDrug toxicityCytochrome P450Cirrhosishepatic leukemia factorfibroblast growth factorsignal transducer and activator of transcription 3Phosphate-buffered salinePartial hepatectomyquantitative reverse transcription polymerase chain reactionCarbon tetrachloridefibroblast growth factor receptor
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Authors
Friederike Böhm, Tobias Speicher, Claus Hellerbrand, Clive Dickson, Juha M. Partanen, David M. Ornitz, Sabine Werner,