| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3298197 | Gastroenterology | 2008 | 21 Pages |
Abstract
These findings provide novel mechanistic insights into epigenetic modulations induced by ROS in the process of carcinogenesis. They are potentially relevant to understanding the activity of ROS in silencing various tumor suppressor genes and in subsequent tumor progression and metastasis.
Keywords
PRXMMP5-Aza-dCGPx1PMSMSPDnmtHDAC5-Aza-2′-deoxycytidineDNA methyltransferaseHCCMAPKROSchromatin immunoprecipitationbisulfite sequencingSODSuperoxide dismutasematrix metalloproteinasehistone deacetylasemitogen-activated protein kinasePeroxiredoxinCHiPHepatocellular carcinomaglutathione peroxidase 1Reactive oxygen species
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Authors
Seung-Oe Lim, Jin-Mo Gu, Min Sook Kim, Hyun-Soo Kim, Young Nyun Park, Cheol Keun Park, Jae Won Cho, Young Min Park, Guhung Jung,