Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3298292 | Gastroenterology | 2008 | 13 Pages |
Abstract
Frequent HDAC2 mutations are found in MSI tumors and HDAC2 plays a major role in mediating apoptotic response to HDAC inhibitors through direct regulation of APAF1.
Keywords
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Gastroenterology
Authors
Christin L. Hanigan, Manon van Engeland, Adriaan P. De Bruine, Kim A. Wouters, Matty P. Weijenberg, James R. Eshleman, James G. Herman,