Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3298298 | Gastroenterology | 2008 | 11 Pages |
Abstract
Our results indicate that host neutralizing responses in HCV-infected patients target viral entry after HCV binding most likely related to HCV-CD81, and HCV-SR-BI interactions, as well as membrane fusion. These findings have implications not only for the understanding of the pathogenesis of HCV infection but also for the design of novel immunotherapeutic and preventive strategies.
Keywords
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Authors
Anita Haberstroh, Eva K. Schnober, Mirjam B. Zeisel, Patric Carolla, Heidi Barth, Hubert E. Blum, François-Loic Cosset, George Koutsoudakis, Ralf Bartenschlager, Ann Union, Erik Depla, Ania Owsianka, Arvind H. Patel, Catherine Schuster,