| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3298369 | Gastroenterology | 2010 | 11 Pages |
Abstract
The lack of excessive local inflammation and alternative activation of macrophages, triggered in part by the agent T whipplei itself, may explain the hallmark of Whipple's disease: invasion of the intestinal mucosa with macrophages incompetent to degrade T whipplei.
Keywords
CFUinducible nitric synthaserRNATNFAAMLPLCCLiNOSmRNAIELmessenger RNARibosomal RNAinterferonIFNinterleukinT helper celltumor necrosis factorlamina propria lymphocytesintraepithelial lymphocytesAlternatively activated macrophagescolony-forming unitspolymerase chain reactionPCRchemokine (C-C motif) ligand 2
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Authors
Verena Moos, Carsten Schmidt, Anika Geelhaar, Désirée Kunkel, Kristina Allers, Katina Schinnerling, Christoph Loddenkemper, Florence Fenollar, Annette Moter, Didier Raoult, Ralf Ignatius, Thomas Schneider,