Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3298372 | Gastroenterology | 2010 | 14 Pages |
Abstract
GUCY2C is a tumor suppressor that controls proliferation and metabolism of intestinal epithelial cells by inactivating AKT signaling. This receptor and its ligands, which are paracrine hormones, might be novel candidates for anticolorectal cancer therapy.
Keywords
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Gastroenterology
Authors
Jieru Egeria Lin, Peng Li, Adam Eugene Snook, Stephanie Schulz, Abhijit Dasgupta, Terry Marie Hyslop, Ahmara Vivian Gibbons, Glen Marszlowicz, Giovanni Mario Pitari, Scott Arthur Waldman,