Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3298373 | Gastroenterology | 2010 | 14 Pages |
Abstract
The tight junction protein claudin-1 has gastric tumor suppressive activity and is a direct transcriptional target of RUNX3. Claudin-1 is down-regulated during the epithelial-mesenchymal transition; RUNX3 might therefore act as a tumor suppressor to antagonize the epithelial-mesenchymal transition.
Keywords
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Gastroenterology
Authors
Ti Ling Chang, Kosei Ito, Tun Kiat Ko, Qiang Liu, Manuel Salto-Tellez, Khay Guan Yeoh, Hiroshi Fukamachi, Yoshiaki Ito,