Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3298377 | Gastroenterology | 2010 | 14 Pages |
Abstract
The peripheral stress mediator norepinephrine induces visceral hypersensitivity to colorectal distension in response to HeCS by increasing the expression of NGF in the colon wall, which sensitizes primary afferents in the absence of an inflammatory response.
Keywords
Related Topics
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Medicine and Dentistry
Gastroenterology
Authors
John H. Winston, Guang-Yin Xu, Sushil K. Sarna,