Article ID Journal Published Year Pages File Type
3308191 Gastrointestinal Endoscopy 2007 5 Pages PDF
Abstract

IntroductionClosure of the gastrotomy when performing transgastric procedures is one of the most challenging steps to overcome. Several methods of gastric closure have been described, but a simple and safe technique is still lacking.AimTo evaluate the technical feasibility and safety of a new method of endoscopic gastric closure using a nitinol septal occluder in a porcine survival model.DesignEndoscopic animal experimental study in a porcine survival model.Materials and MethodsIn 6 male pigs under general anesthesia, a 1-cm full-thickness gastrotomy was performed on the anterior body of the stomach and closed with a nitinol septal occluder (Occlutech). Postoperative follow-up included endoscopy and laparoscopy at 1, 2, 4, and 6 weeks after the initial procedure and endoscopy alone at weeks 8, 10, and 12.ResultsAll of the gastrotomy closures with the septal occluder were successful. At follow-up endoscopy and laparoscopy there were no signs of adhesions, peritonitis, or perigastric abscess formation at the gastrotomy site. At 12 weeks, 5 of 6 animals were thriving, with appropriate weight gain.ConclusionsEndoscopic gastrotomy closure with a septal occluder is technically feasible, safe, and effective in a survival porcine model.

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