| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3314617 | Journal of Hepatology | 2007 | 8 Pages |
Abstract
Although both PPT and DPN decreased hepatic injury following trauma-hemorrhage, ER-α agonist PPT appears to be more effective in downregulating NF-κB and AP-1 activity, and iNOS induction. Thus, ER-α appears to play a predominant role in mediating the salutary effects of E2 in ameliorating hepatic damage following trauma-hemorrhage.
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Authors
Tomoharu Shimizu, Huang-Ping Yu, Takao Suzuki, László Szalay, Ya-Ching Hsieh, Mashkoor A. Choudhry, Kirby I. Bland, Irshad H. Chaudry,