| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3314971 | Journal of Hepatology | 2006 | 8 Pages |
Background/AimsIn France, geographic access to medical care may affect the diagnosis of hepatitis C. The aims of this study were to compare the detection rates of hepatitis C in urban and rural areas after adjusting for distance to medical care, and evaluating the impact of the place of residence on patients' clinical characteristics.MethodsBetween 1994 and 2001, 1938 newly detected cases were recorded in a French population of 1,005,817 inhabitants. Age and sex-adjusted detection rates for 105 inhabitants were estimated for urban and rural areas and for classes of distance to the nearest practitioner.ResultsDetection rates were lower in rural than in urban areas [14.1, (95CI: 12.5–15.7) versus 24.7, (95CI: 23.5–26.0)] and decreased as the distance to the general practitioner increased [27.0, (95CI: 25.5–28.4) versus 13.7, (95CI: 12.1–15.3) for a cutoff value of 1.5 km]. In multivariate analyses, detection rates were only influenced by the distance to general practitioner. Hepatocellular carcinoma at diagnosis was more frequent among rural than among urban patients (adjusted OR=2.28, 95CI: 0.97–5.39, P=0.059).ConclusionsA poorer geographic access to care explained the lower detection of hepatitis C in rural areas. Hepatocellular carcinoma was more frequent in rural patients. It may result from later detection and/or involvement of environmental factors on hepatocarcinogenesis.
