Article ID Journal Published Year Pages File Type
3314981 Journal of Hepatology 2006 10 Pages PDF
Abstract
CpG-containing DNA-sequences induce early hepatic injury, but mediate long-term protection against LPS hepatotoxicity. The mechanism of protection is based on the induction of cross-tolerance, probably via inhibition of the downstream TRAF6-NFκB signaling pathway and upregulation of the TLR4 surface receptor.
Related Topics
Health Sciences Medicine and Dentistry Gastroenterology
Authors
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