Article ID Journal Published Year Pages File Type
3315618 Journal of Hepatology 2006 6 Pages PDF
Abstract
These findings demonstrate that skeletal muscle adapts, through a rapid induction of glutamine synthetase, to increase its capacity for removal of blood-borne ammonia in acute liver failure. Maintenance of muscle mass together with the development of agents with the capacity to stimulate muscle glutamine synthetase could provide effective ammonia-lowering strategies in this disorder.
Related Topics
Health Sciences Medicine and Dentistry Gastroenterology
Authors
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