Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3316616 | Pancreatology | 2013 | 7 Pages |
Abstract
The present study demonstrated that miR-181b was associated with the resistance of pancreatic cancer cells to gemcitabine, and verified that miR-181b enhances the activity of NF-κB by inhibiting CYLD, leading to the resistance to gemcitabine. Our results suggest that miR-181b is a potential target for decreasing gemcitabine resistance.
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Authors
Daisuke Takiuchi, Hidetoshi Eguchi, Hiroaki Nagano, Yoshifumi Iwagami, Yoshito Tomimaru, Hiroshi Wada, Koichi Kawamoto, Shogo Kobayashi, Shigeru Marubashi, Masahiro Tanemura, Masaki Mori, Yuichiro Doki,