Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3317875 | Pancreatology | 2012 | 6 Pages |
Abstract
TNFA promoter variants do not alter susceptibility to AP, but rather the TNFâα expression-enhancing â1031C and â863A alleles significantly increased the risk of AP progression to MODS. These data, within the context of previous studies, clarify the risk of specific genetic variants in TNFA and therefore the role of TNFâα in the overall AP syndrome.
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Authors
Faraz Bishehsari, Arun Sharma, Kimberly Stello, Chad Toth, Michael Richard O'Connell, Anna C. Evans, Jessica LaRusch, Venkata Muddana, Georgios I. Papachristou, David C. Whitcomb,