Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3319274 | Seminars in Colon and Rectal Surgery | 2013 | 4 Pages |
Abstract
Adjuvant preoperative therapy for rectal cancer is delivered by two fractionation schedules: short-course radiation and long-course chemoradiation. Patients selected for treatment with short-course radiation included those with cT1-3 disease, whereas those selected for chemoradiation include cT3 and/or N+ disease. Therefore, retrospective comparisons were not possible. There are two randomized trials that have included patients with cT3 and/or N+ disease as well delivered sequential or postoperative chemotherapy thereby allowing a more relevant comparison with chemoradiation. New trials of short-course radiation have included patients with stages cT3 and/or N+ as well delivered sequential or chemotherapy.
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Authors
Bruce D. MD,