Acute kidney injury after hip fracture surgery among aging population: Evaluation of incidence and covariates

PurposeAcute kidney injury (AKI) is a serious complication after hip fracture surgery in aging population. This study was conducted to determine the incidence of acute kidney injury and the associated risk factors.MethodsIn a retrospective cohort of 214 patients hospitalized for hip fracture having undergone surgery, we examined the incidence of acute kidney injury defined according to the RIFLE (risk, injury, failure, loss, end stage kidney disease) Criteria and factors contributing to AKI.ResultsAmong the included 214 patients, AKI occurred in 36 cases (16.8%), at the most two days after admission, and all patients recovered to their baseline serum creatinine levels within 8 days. The number of patients undergoing renal replacement therapy (RRT) was three (1.40%), with no need of replacement therapy on hospital discharge. The baseline estimated glomerular filtration rate (eGFR), serum potassium levels at admission, and female sex were determined to be independent predictors of AKI development (OR = 0.959, 95% CI, 0.93–0.98; OR = 2.76, 95% CI, 1.24–6.14; and OR = 0.377, 95% CI, 0.34–5.14, respectively).ConclusionAKI was a frequent event after surgery for hip fracture and, although transient, was associated with longer hospitalization. Baseline renal function was an independent predictor. AKI in hip fracture patients should be managed collaboratively by orthopedists and nephrologists to increase our knowledge and improve clinical approach.