Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3325996 | NPG Neurologie - Psychiatrie - Gériatrie | 2015 | 7 Pages |
Abstract
In dementia syndromes, adverse drug reactions (ADRs) are often non-specific (e.g. behavioural disorders) and can lead to inappropriate prescribing, resulting in iatrogenic effects. Only a few studies on ADRs have been conducted in this population. We therefore set up a prospective descriptive study in an acute care unit specialised in the management of demented subjects, in order to describe ADRs according to the severity and suspected drug. From a total of 293 patients (82 ± 8 y), 70 had reported at least one ADR; half of these ADRs were serious. The most frequent ADRs were neurological (16%), psychiatric (15%), and nephrological (11%). The drugs most often suspected, regardless of the severity of ADRs, were those of the central nervous system.
Keywords
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Authors
L. MD, MPH, M. PhD, MD, MPH, T. PhD, MD, J.-L. PhD, MD, MPH, C. MD, MPH, P. PhD, MD, MPH, P.-O. PhD, MD, MPH, D. PhD, MD, MPH, R. MSc, MD,