Efficacité des vaccins antigrippes chez la personne âgée

Annual vaccination is considered to be the cornerstone for preventing seasonal influenza infections. Trivalent inactivated influenza virus vaccines (TIV) are believed to be not only effective but also cost-effective. Although they effectively prevent 70 to 90% of infections in adults, the measurement of their efficacy in the older adult population appears to be less precise and is still a controversial subject. From recent meta-analyses, this review will aim to examine how effective current TIV really are in the older adult, and analyze the most important factors that have biased the benefits measured in this population. Finally, this review concludes with practical recommendations and possible strategies to improve the assessment of the true benefits of influenza vaccines in the aged population.