La paralysie supranucléaire progressive : un diagnostic méconnu en gériatrie

Progressive supranuclear palsy (PSP) is a very rare disease in young adults, but might be encountered in older adults. PSP diagnosis should be discussed in patients older than 60 years, with extrapyramidal syndrome, which resist to levodopa, cognitive impairment, and/or vertical supranuclear palsy. The diagnosis is mainly done by clinical signs, and can be confirmed by RMI and/or oculography. There is a mean delay of two years to make the diagnosis of this disease, often wrongly diagnosed as Parkinson disease, and treated as if it was. There is no efficient treatment at the moment, but symptomatic therapeutics are usefulness. The prognostic of PSP is bad, and median survival of these patients is about 10 years.