Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
332638 | Psychiatry Research | 2007 | 5 Pages |
Abstract
We examined the relationship between a history of obstetric complications (OCs) and the number of neurological soft signs (NSS) in a group of 132 patients experiencing their first episode of psychosis. We measured NSS by means of a comprehensive standardized assessment and gained information on a selection of nine OCs from the patient's mother. Contrary to our expectations we found significantly more NSS in the group of patients without a history of OCs. This effect was independent of medication in the group of patients with a schizophrenic disorder, but not in the entire group. It is possible that the patients with a history of OCs carry fewer genes for schizophrenia (and NSS) and ‘needed’ the OCs to develop schizophrenia.
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Authors
Marco P.M. Boks, Jean-Paul Selten, Stuart Leask, Stynke Castelein, Robert J. van den Bosch,