Article ID Journal Published Year Pages File Type
3326410 NPG Neurologie - Psychiatrie - Gériatrie 2009 5 Pages PDF
Abstract
Semantic memory concerns concept and knowledge. It is robust with age. It is altered at the onset of Alzheimer's disease. Semantic dementia (SD) is a syndrome of progressive loss of semantic knowledge for objects and people. A diagnosis of typical SD relies on an isolated and progressive loss of semantic knowledge, attested by a deficit of word comprehension and a deficit of objects and/or people identification, with imaging showing temporal atrophy and/or hypometabolism. SD is atypical if the deficit of semantic knowledge is present only within a single modality (verbal vs visual), or if non semantic deficits (mild and not present at onset) and/or neurological signs, are associated with the semantic loss.
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