Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3329678 | Critical Reviews in Oncology/Hematology | 2009 | 10 Pages |
Abstract
Taxanes are very effective agents in several types of cancer. However, their activity is counterbalanced by side effects that could represent a limitation of their use in older cancer patients. This review aims at evaluating whether or not there are data supporting a tailored use of standard taxanes i.e. docetaxel and paclitaxel in elderly patients with the aim to increase their therapeutic index. In addition, recent data on the role of nanoparticle albumine-bound paclitaxel in breast cancer are discussed in this paper.
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Authors
Laura Biganzoli, Sara Licitra, Erica Moretti, Marta Pestrin, Elena Zafarana, Angelo Di Leo,